Lipid in microglial biology — from material to mediator-Reference-Cited by-同舟云学术

Lipid in microglial biology — from material to mediator

Published:2023-07-17 Issue:1 Volume:43 Page:
ISSN:1880-8190
Container-title:Inflammation and Regeneration
language:en
Short-container-title:Inflamm Regener

Author:

Yamamoto Shota,Masuda Takahiro^ORCID

Abstract

AbstractMicroglia are resident macrophages in the central nervous system (CNS) that play various roles during brain development and in the pathogenesis of CNS diseases. Recently, reprogramming of cellular energetic metabolism in microglia has drawn attention as a crucial mechanism for diversification of microglial functionality. Lipids are highly diverse materials and crucial components of cell membranes in every cell. Accumulating evidence has shown that lipid and its metabolism are tightly involved in microglial biology. In this review, we summarize the current knowledge about microglial lipid metabolism in health and disease.

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

https://link.springer.com/content/pdf/10.1186/s41232-023-00289-z.pdf

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