Association between different anti-Tat antibody isotypes and HIV disease progression: data from an African cohort

Author:

Nicoli Francesco,Chachage Mkunde,Clowes Petra,Bauer Asli,Kowour Dickens,Ensoli Barbara,Cafaro Aurelio,Maboko Leonard,Hoelscher Michael,Gavioli Riccardo,Saathoff Elmar,Geldmacher Christof

Funder

European Commission + Regione Emilia Romagna

Consorzio Italiano Biotecnologie

European Commission

EC 7th Framework Programme

Università degli Studi di Ferrara (IT)

DFG (German Research Foundation)

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases

Reference65 articles.

1. Berkhout B, Silverman RH, Jeang KT. Tat trans-activates the human immunodeficiency virus through a nascent RNA target. Cell. 1989;59(2):273–82.

2. Zauli G, Gibellini D, Celeghini C, Mischiati C, Bassini A, La Placa M, et al. Pleiotropic effects of immobilized versus soluble recombinant HIV-1 Tat protein on CD3-mediated activation, induction of apoptosis, and HIV-1 long terminal repeat transactivation in purified CD4+ T lymphocytes. J Immunol. 1996;157(5):2216–24.

3. Li CJ, Ueda Y, Shi B, Borodyansky L, Huang L, Li YZ, et al. Tat protein induces self-perpetuating permissivity for productive HIV-1 infection. Proc Natl Acad Sci U S A. 1997;94(15):8116–20.

4. Secchiero P, Zella D, Capitani S, Gallo RC, Zauli G. Extracellular HIV-1 tat protein up-regulates the expression of surface CXC-chemokine receptor 4 in resting CD4+ T cells. J Immunol. 1999;162(4):2427–31.

5. Monini P, Cafaro A, Srivastava IK, Moretti S, Sharma VA, Andreini C, et al. HIV-1 Tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies. PLoS One. 2012;7(11):e48781.

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