Author:
Serin Istemi,Sari Nagehan Didem,Gunaltili Murat,Karakilic Ayse,Gulesir Begum,Kal Kolik Beyza,Cevik Gulnihal,Sungurlu Hilal,Keskin Melike,Baltik Muhammed,Cakmak Onurhan,Cinli Tahir Alper
Abstract
Abstract
Background
Severe inflammation and one or more extrapulmonary organ dysfunctions have been reported and this clinical picture is defined as "multisystem inflammatory syndrome in adults" (MIS-A) in severe coronavirus disease-2019 (COVID-19). We aimed to determine the effect of LDH/lymphocyte ratio (LLR) on the development of MIS-A.
Methods
The data of 2333 patients were retrospectively analyzed.
Results
MIS-A rate was found to be 9.9% and MIS-A related mortality was 35.3%. LRR level above 0.24 was found to predict MIS-A development with 70% sensitivity and 65.2% specificity. The risk of MIS-A development was found to be 3.64 times higher in those with LRR levels above 0.24 compared to those with 0.24 and below. In patients with MIS-A, LRR level above 0.32 predicts mortality with 78% sensitivity and 70% specificity.
Conclusions
Early detection of MIS-A with high sensitivity and specificity in a practical ratio is very important in terms new studies.
Publisher
Springer Science and Business Media LLC
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