Multisystem Inflammatory Syndrome in Adults (MIS-A) and SARS-CoV2: An Evolving Relationship

Author:

Worku Dominic12ORCID

Affiliation:

1. Infectious Diseases Department, Morriston Hospital, Heol Maes Eglwys, Morriston SA6 6NL 1, UK

2. Public Health Wales, Cardiff CF10 4BZ, UK

Abstract

The SARS-CoV2 pandemic is the most significant global health emergency of the last century. While the pathophysiology of SARS-CoV2 is understood, the early and long-term outcomes of natural infection are increasingly being recognised. Multisystem inflammatory syndrome (MIS) represents a manifestation of the extreme immune dysfunction that SARS-CoV2 infection heralds and has been described in both children (MIS-C) and adults (MIS-A). Here, we discuss current knowledge of MIS-A and the vast questions that remain unanswered.

Publisher

MDPI AG

Subject

General Engineering

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