Author:
Gutiérrez Juan Pablo,Cervantes Isabel,Molina Antonio,Valera Mercedes,Goyache Félix
Abstract
Abstract
We present here a simple approach to obtain reliable estimates of the effective population size in real world populations via the computation of the increase in inbreeding for each individual (delta F
i
) in a given population. The values of delta F
i
are computed as t-root of 1 - (1 - F
i
) where F
i
is the inbreeding coefficient and t is the equivalent complete generations for each individual. The values of delta F computed for a pre-defined reference subset can be averaged and used to estimate effective size. A standard error of this estimate of N
e can be further computed from the standard deviation of the individual increase in inbreeding. The methodology is demonstrated by applying it to several simulated examples and to a real pedigree in which other methodologies fail when considering reference subpopulations. The main characteristics of the approach and its possible use are discussed both for predictive purposes and for analyzing genealogies.
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Animal Science and Zoology,General Medicine,Ecology, Evolution, Behavior and Systematics
Cited by
122 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献