How does heparin prevent the pH inactivation of cathepsin B? Allosteric mechanism elucidated by docking and molecular dynamics
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Biotechnology
Link
http://link.springer.com/content/pdf/10.1186/1471-2164-11-S5-S5.pdf
Reference58 articles.
1. Chapman HA, Riese RJ, Shi GP: Emerging roles for cysteine proteases in human biology. Annual review of physiology. 1997, 59: 63-88. 10.1146/annurev.physiol.59.1.63.
2. Lutgens SP, Cleutjens KB, Daemen MJ, Heeneman S: Cathepsin cysteine proteases in cardiovascular disease. Faseb J. 2007, 21 (12): 3029-3041. 10.1096/fj.06-7924com.
3. McKerrow JH: Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action. International journal for parasitology. 1999, 29 (6): 833-837. 10.1016/S0020-7519(99)00044-2.
4. Haque A, Banik NL, Ray SK: New insights into the roles of endolysosomal cathepsins in the pathogenesis of Alzheimer's disease: cathepsin inhibitors as potential therapeutics. CNS & neurological disorders drug targets. 2008, 7 (3): 270-277. 10.2174/187152708784936653.
5. Martel-Pelletier J, Cloutier JM, Pelletier JP: Cathepsin B and cysteine protease inhibitors in human osteoarthritis. J Orthop Res. 1990, 8 (3): 336-344. 10.1002/jor.1100080305.
Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. In silico approaches for better understanding cysteine cathepsin-glycosaminoglycan interactions;Carbohydrate Research;2024-09
2. Characterization of a novel dipeptidyl peptidase 1 of Trichinella spiralis and its participation in larval invasion;Acta Tropica;2024-01
3. Microglial P2X4 receptors promote ApoE degradation and contribute to memory deficits in Alzheimer’s disease;Cellular and Molecular Life Sciences;2023-05
4. Antioxidant and anticoagulant activity of crude polysaccharide and α-L-Rhamnose from Grateloupia lithophila;Biomass Conversion and Biorefinery;2022-12-29
5. Engaging the Lysosome and Lysosome-Dependent Cell Death in Cancer;Breast Cancer;2022-08-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3