Evaluation of the novel liver micronucleus assay using formalin-fixed tissues

Author:

Hamada ShuichiORCID,Shigano Miyuki,Kawakami Satoru,Ueda Maya,Sui Hajime,Yamada Katsuya,Hagio Soichiro,Momonami Ayaka,Maeda Akihisa,Terashima Yukari,Ohyama Wakako,Morita Takeshi,Hayashi Makoto

Publisher

Springer Science and Business Media LLC

Subject

Environmental Science (miscellaneous),Genetics,Social Psychology

Reference40 articles.

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2. Natarajan AT, Tates AD, Van Buul PP, Meijers M, NDe V. Cytogenetic effects of mutagens/carcinogens after activation in a microsomal system in vitro I. induction of chromosome aberrations and sister chromatid exchanges by diethylnitrosamine (DEN) and dimethylnitrosamine (DMN) in CHO cells in the presence of rat-liver microsomes. Mutat Res. 1976;37:83–90.

3. Ashby J, Tennant RW. Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U. S. NTP. Mutat Res. 1991;257:229–306.

4. Morita T, Asano N, Awogi T, Sasaki YF, Sato S, Shimada S, Sutou S, Suzuki T, Wakata A, Sofuni T, Hayashi M. Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (group 1, 2A and 2B). The summary report of the 6th collaborative study by CSGMT/JEMS∙MMS. Mutat Res. 1997;389:3–122.

5. George E, Westmoreland C. Evaluation of the in vivo genotoxicity of the structural analogues 2,6-diaminotoluene using the rat micronucleus test and rat liver UDS assay. Carcinogenesis. 1991;12:2233–7.

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