Author:
Park Ji-Yeon,Kim Siyong,Park Hae-Jin,Lee Jeong-Woo,Kim Yeon-Sil,Suh Tae-Suk
Abstract
Abstract
Purpose
To recommend the optimal plan parameter set of grid size and angular increment for dose calculations in treatment planning for lung stereotactic body radiation therapy (SBRT) using dynamic conformal arc therapy (DCAT) considering both accuracy and computational efficiency.
Materials and methods
Dose variations with varying grid sizes (2, 3, and 4 mm) and angular increments (2°, 4°, 6°, and 10°) were analyzed in a thorax phantom for 3 spherical target volumes and in 9 patient cases. A 2-mm grid size and 2° angular increment are assumed sufficient to serve as reference values. The dosimetric effect was evaluated using dose–volume histograms, monitor units (MUs), and dose to organs at risk (OARs) for a definite volume corresponding to the dose–volume constraint in lung SBRT. The times required for dose calculations using each parameter set were compared for clinical practicality.
Results
Larger grid sizes caused a dose increase to the structures and required higher MUs to achieve the target coverage. The discrete beam arrangements at each angular increment led to over- and under-estimated OARs doses due to the undulating dose distribution. When a 2° angular increment was used in both studies, a 4-mm grid size changed the dose variation by up to 3–4% (50 cGy) for the heart and the spinal cord, while a 3-mm grid size produced a dose difference of <1% (12 cGy) in all tested OARs. When a 3-mm grid size was employed, angular increments of 6° and 10° caused maximum dose variations of 3% (23 cGy) and 10% (61 cGy) in the spinal cord, respectively, while a 4° increment resulted in a dose difference of <1% (8 cGy) in all cases except for that of one patient. The 3-mm grid size and 4° angular increment enabled a 78% savings in computation time without making any critical sacrifices to dose accuracy.
Conclusions
A parameter set with a 3-mm grid size and a 4° angular increment is found to be appropriate for predicting patient dose distributions with a dose difference below 1% while reducing the computation time by more than half for lung SBRT using DCAT.
Publisher
Springer Science and Business Media LLC
Subject
Radiology, Nuclear Medicine and imaging,Oncology
Reference27 articles.
1. Videtic GM, Signh AK, Chang JY, Le QT, Parker W, Oliver KR, Schild SE, Hu C: A Randomized phase II study 2 comparing sterotactic body radiation therapy (SBRT) schedules for medically inoperable patients with stage I peripheral non-small cell lung cancer. Radiation Therapy Oncology Group http://www.rtog.org/ClinicalTrials/ProtocolTable/StudyDetails.aspx?action=openFile&FileID=4673
2. Timmerman R, Abdulrahman R, Kavanagh BD, Meyer J: Lung cancer: a model for implementing stereotactic body radiation therapy into practice. In IMRT, IGRT, SBRT: advanced in the treatment planning and delivery of radiotherapy. Edited by: Meyer JL, Kavanagh JA, Purdy JA, Timmerman R. Basel: Karger; 2007:367-385.
3. Solberg TD, Boedeker KL, Fogg R, Selch MT, DeSalles AA: Dynamic arc radiosurgery field shaping: a comparison with static field conformal and noncoplanar circular arcs. Int J Radiat Oncol Biol Phys 2001, 49: 1481-1491. 10.1016/S0360-3016(00)01537-6
4. Holt A, van Vliet-Vroegindeweij C, Mans A, Belderbos JS, Damen EM: Volumetric-modulated arc therapy for stereotactic body radiotherapy of lung tumors: a comparison with intensity-modulated radiotherapy techniques. Int J Radiat Oncol Biol Phys 2011, 81: 1560-1567. 10.1016/j.ijrobp.2010.09.014
5. Buyyounouski MK, Balter P, Lewis B, D’Ambrosio DJ, Dilling TJ, Miller RC, Schefter T, Tome W, Harris EE, Price RA Jr, et al.: Stereotactic body radiotherapy for early-stage non-small-cell lung cancer: report of the ASTRO emerging technology committee. Int J Radiat Oncol Biol Phys 2010, 78: 3-10. 10.1016/j.ijrobp.2010.04.010
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