Author:
Grözinger Sven Oliver,Bert Christoph,Haberer Thomas,Kraft Gerhard,Rietzel Eike
Abstract
Abstract
Background
Intrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target motion by tracking with the treatment beam.
Methods
Lateral motion components were compensated directly with the beam scanning system by adapting nominal beam positions according to the target motion. Longitudinal motion compensation to mitigate motion induced range changes was performed with a dedicated wedge system that adjusts effective particle energies at isocenter.
Results
Lateral compensation performance was better than 1% for a homogeneous dose distribution when comparing irradiations of a stationary radiographic film and a moving film using motion compensation. The accuracy of longitudinal range compensation was well below 1 mm.
Conclusion
Motion compensation with scanned particle beams is technically feasible with high precision.
Publisher
Springer Science and Business Media LLC
Subject
Radiology, Nuclear Medicine and imaging,Oncology
Reference48 articles.
1. ICRU: Report 50. Bethesda, Md, USA, International Commission on Radiation Units and Measurements; 1993.
2. ICRU: Report 62. Bethesda, Md, USA, International Commission on Radiation Units and Measurements; 1999.
3. Phillips MH, Pedroni E, Blattmann H, Boehringer T, Coray A, Scheib S: Effects of respiratory motion on dose uniformity with a charged particle scanning method. Phys Med Biol 1992, 37: 223-233. 10.1088/0031-9155/37/1/016
4. Grozinger SO, Rietzel E, Li Q, Bert C, Haberer T, Kraft G: Simulations to design an online motion compensation system for scanned particle beams. Phys Med Biol 2006, 51: 3517-3531. 10.1088/0031-9155/51/14/016
5. Bert C, Grözinger SO, Rietzel E: Quantification of interplay effects of scanned particle beams and moving targets. Phys Med Biol 2008, 53: 2253-2265. 10.1088/0031-9155/53/9/003
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