Transforming growth factor-β and breast cancer: Lessons learned from genetically altered mouse models
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Springer Science and Business Media LLC
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http://link.springer.com/content/pdf/10.1186/bcr41.pdf
Reference35 articles.
1. Robinson SD, Silberstein GB, Roberts AB, Flanders KC, Daniel CW: Regulated expression and growth inhibitory effects of transforming growth factor-β isoforms in mouse mammary gland development. Development. 1991, 113: 867-878. This paper describes the expression patterns of the TGF-b isoforms during different stages of mammary development, and the differential effects of exogenous TGF-bs on ductal and alveolar cells.
2. Hosobuchi M, Stampfer MR: Effects of transforming growth factor β on growth of human mammary epithelial cells in culture. In Vitro Cell Dev Biol. 1989, 25: 705-713.
3. Daniel CW, Silberstein GB, Van Horn K, Strickland P, Robinson S: TGF-β1-induced inhibition of mouse mammary ductal growth: developmental specificity and characterization. Dev Biol. 1989, 135: 20-30.
4. Reiss M, Barcellos-Hoff MH: Transforming growth factor-β in breast cancer: a working hypothesis. Breast Cancer Res Treat. 1997, 45: 81-95. 10.1023/A:1005865812918.
5. Gobbi H, DuPont WD, Simpson JF, et al: Relationship between TGF-β type II receptor expression and breast cancer risk in women with epithelial hyperplasia lacking atypia. J Natl Cancer Inst. 1999, 91: 2096-2101. 10.1093/jnci/91.24.2096. This immunohistochemical study of TGF-β type II receptor expression in human breast hyperplasias suggests that decreased expression of TGF-β receptors may be a significant early event in the genesis of human breast cancer.
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