High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis-Reference-Cited by-同舟云学术

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High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis

Published:2016-11-22 Issue:1 Volume:8 Page:
ISSN:1756-994X
Container-title:Genome Medicine
language:en
Short-container-title:Genome Med

Author:

Gomez-Cabrero David,Almgren Malin,Sjöholm Louise K.,Hensvold Aase H.,Ringh Mikael V.,Tryggvadottir Rakel,Kere Juha,Scheynius Annika,Acevedo Nathalie,Reinius Lovisa,Taub Margaret A.,Montano Carolina,Aryee Martin J.,Feinberg Jason I.,Feinberg Andrew P.,Tegnér Jesper,Klareskog Lars,Catrina Anca I.,Ekström Tomas J.

Funder

AFA Försäkring

Vetenskapsrådet

Swedish Rheumatism Association

Swedish Research Foundation of Strategic Research

STATegra EU FP7 project

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1186/s13073-016-0374-0.pdf

Reference50 articles.

1. Feinberg AP. Phenotypic plasticity and the epigenetics of human disease. Nature. 2007;447:433–40.

2. Liu Y, Aryee MJ, Padyukov L, Fallin MD, Hesselberg E, Runarsson A, Reinius L, Acevedo N, Taub M, Ronninger M, et al. Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol. 2013;31:142–7 ( http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE42861 ).

3. Marsit CJ. Influence of environmental exposure on human epigenetic regulation. J Exp Biol. 2015;218:71–9.

4. Irizarry RA, Ladd-Acosta C, Wen B, Wu Z, Montano C, Onyango P, Cui H, Gabo K, Rongione M, Webster M, et al. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet. 2009;41:178–86.

5. Ziller MJ, Gu H, Muller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, et al. Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013;500:477–81.

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