Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

Author:

Mordmüller Benjamin,Supan Christian,Sim Kim Lee,Gómez-Pérez Gloria P,Ospina Salazar Carmen Lucelly,Held Jana,Bolte Stefanie,Esen Meral,Tschan Serena,Joanny Fanny,Lamsfus Calle Carlos,Löhr Sascha JZ,Lalremruata Albert,Gunasekera Anusha,James Eric R,Billingsley Peter F,Richman Adam,Chakravarty Sumana,Legarda Almudena,Muñoz Jose,Antonijoan Rosa M,Ballester Maria Rosa,Hoffman Stephen L,Alonso Pedro L,Kremsner Peter G

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Parasitology

Reference35 articles.

1. WHO. World Malaria Report 2014. Geneva: World Health Organization; 2014.

2. Mordmüller B, Kremsner PG. Malarial parasites vs. antimalarials: never-ending rumble in the jungle. Curr Mol Med. 2006;6:247–51.

3. Sauerwein RW, Roestenberg M, Moorthy VS. Experimental human challenge infections can accelerate clinical malaria vaccine development. Nat Rev Immunol. 2011;11:57–64.

4. Fairley H. Chemotherapeutic suppression and prophylaxis in malaria. Trans R Soc Trop Med Hyg. 1945;38:311–55.

5. Verhage DF, Telgt DSC, Bousema JT, Hermsen CC, van Gemert GJA, van der Meer JWM, et al. Clinical outcome of experimental human malaria induced by Plasmodium falciparum-infected mosquitoes. Neth J Med. 2005;63:52–8.

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