Sporozoite immunization: innovative translational science to support the fight against malaria

Author:

Richie Thomas L.1ORCID,Church L. W. Preston1ORCID,Murshedkar Tooba1,Billingsley Peter F.1ORCID,James Eric R.1ORCID,Chen Mei-Chun1,Abebe Yonas1,Natasha KC 1,Chakravarty Sumana1,Dolberg David1,Healy Sara A.2ORCID,Diawara Halimatou3,Sissoko Mahamadou S.3ORCID,Sagara Issaka3ORCID,Cook David M.2ORCID,Epstein Judith E.2ORCID,Mordmüller Benjamin45ORCID,Kapulu Melissa67ORCID,Kreidenweiss Andrea58ORCID,Franke-Fayard Blandine9ORCID,Agnandji Selidji T.910ORCID,López Mikue María-Silvia A.11,McCall Matthew B. B.4510ORCID,Steinhardt Laura12ORCID,Oneko Martina13ORCID,Olotu Ally14ORCID,Vaughan Ashley M.1516ORCID,Kublin James G.1718ORCID,Murphy Sean C.1920ORCID,Jongo Said14,Tanner Marcel2122ORCID,Sirima Sodiomon B.23ORCID,Laurens Matthew B.24ORCID,Daubenberger Claudia2122ORCID,Silva Joana C.2526ORCID,Lyke Kirsten E.24ORCID,Janse Chris J.9ORCID,Roestenberg Meta927ORCID,Sauerwein Robert W.4ORCID,Abdulla Salim14,Dicko Alassane3ORCID,Kappe Stefan H. I.1516ORCID,Sim B. Kim Lee1ORCID,Duffy Patrick E.2ORCID,Kremsner Peter G.5810ORCID,Hoffman Stephen L.1ORCID

Affiliation:

1. Sanaria Inc, Rockville, MD, USA

2. Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA

3. Malaria Research and Training Center, Mali-NIAID ICER, University of Science, Techniques and Technologies of Bamako, Bamako, Mali

4. Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands

5. Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany

6. Biosciences Department, Kenya Medical Research Institute KEMRI-Wellcome Research Programme, Kilifi, Kenya

7. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK

8. German Center for Infection Research (DZIF), partner site Tübingen, Tübingen, Germany

9. Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands

10. Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon

11. Ministry of Health and Social Welfare, Government of Equatorial Guinea, Malabo, Equatorial Guinea

12. Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA

13. Kenya Medical Research Institute, Centre for Global Health Research, Kisumu, Kenya

14. Bagamoyo Research and Training Center, Ifakara Health Institute, Bagamoyo, Tanzania

15. Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, WA, USA

16. Department of Pediatrics, University of Washington, Seattle, WA, USA

17. Department of Global Health, University of Washington, Seattle, WA, USA

18. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA

19. Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA

20. Center for Emerging and Re-emerging Infectious Diseases and Department of Microbiology, University of Washington, Seattle, WA, USA

21. Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland

22. University of Basel, Basel, Switzerland

23. Groupe de Recherche Action en Santé (GRAS), Ouagadougou, Burkina Faso

24. Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA

25. Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA

26. Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA

27. Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

Funder

European Union/European and Developing Countries Clinical Trials Partnership

MIMVC-Africa and from the German Centre for Infection Research

Intramural Research Program of the National Institute of Allergy and Infectious Diseases, National Institutes of Health

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Immunology

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