S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1-Reference-Cited by-同舟云学术

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S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1

Published:2019-04-18 Issue:1 Volume:20 Page:
ISSN:1471-2369
Container-title:BMC Nephrology
language:en
Short-container-title:BMC Nephrol

Author:

Chen Wei,Xiang Hong,Chen Ruifang,Yang Jie,Yang Xiaoping,Zhou Jianda,Liu Hengdao,Zhao Shaoli,Xiao Jie,Chen Pan,Chen Alex F.,Chen Shuhua,Lu Hongwei

Funder

the National Natural Science Foundation of China

the key research and development project of Hunan Province

Publisher

Springer Science and Business Media LLC

Subject

Nephrology

Link

http://link.springer.com/content/pdf/10.1186/s12882-019-1323-0.pdf

Reference36 articles.

1. Rosen H, Stevens RC, Hanson M, Roberts E, Oldstone MB. Sphingosine-1-phosphate and its receptors: structure, signaling, and influence. Annu Rev Biochem. 2013;82:637–62.

2. Waeber C. Sphingosine 1-phosphate (S1P) signaling and the vasculature. Lysophospholipid Receptors: Signaling and Biochemistry. 2013:313–47.

3. Lorenz JN, Arend LJ, Robitz R, Paul RJ, MacLennan AJ. Vascular dysfunction in S1P₂ sphingosine 1-phosphate receptor knockout mice. Am J Physiol Regul Integr Comp Physiol. 2007;292(1):R440–R6.

4. Liu H, Peng H, Chen S, Liu Y, Xiang H, Chen R, et al. S1PR2 antagonist protects endothelial cells against high glucose-induced mitochondrial apoptosis through the Akt/GSK-3beta signaling pathway. Biochem Biophys Res Commun. 2017;490(3):1119–24.

5. Windh RT, Lee MJ, Hla T, An S, Barr AJ, Manning DR. Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G (12) families of heterotrimeric G proteins. J Biol Chem. 1999;274(39):27351–8.

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