Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production-Reference-Cited by-同舟云学术

Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production

Published:2018-09-14 Issue:1 Volume:19 Page:
ISSN:1471-2172
Container-title:BMC Immunology
language:en
Short-container-title:BMC Immunol

Author:

Lin Li-Rong,Liu Wei,Zhu Xiao-Zhen,Chen Yu-Yan,Gao Zheng-Xiang,Gao Kun,Tong Man-Li,Zhang Hui-Lin,Xiao Yao,Li Wen-Dong,Li Shu-Lian,Lin Hui-Ling,Liu Li-Li,Fang Zan-Xi,Niu Jian-Jun,Lin Yong,Yang Tian-Ci^ORCID

Funder

the National Natural Science Foundation

he National Science Foundation for Distinguished Young Scholars of Fujian

the Youth Foundation Project of Fujian Provincial Health Department

the Medical Innovation Project of Fujian Health Development Planning Commission

the Natural Science Foundation of Fujian Province

the Major Special Projects of Serious Illness in Xiamen

Publisher

Springer Science and Business Media LLC

Subject

Immunology

Link

http://link.springer.com/content/pdf/10.1186/s12865-018-0265-9.pdf

Reference25 articles.

1. Tong ML, Zhao Q, Liu LL, Zhu XZ, Gao K, Zhang HL, Lin LR, Niu JJ, Ji ZL, Yang TC. Whole genome sequence of the Treponema pallidum subsp. pallidum strain Amoy: an Asian isolate highly similar to SS14. PLoS One. 2017;12(8):e0182768.

2. Gao K, Shen X, Lin Y, Zhu XZ, Lin LR, Tong ML, Xiao Y, Zhang HL, Liang XM, Niu JJ. Origin of Nontreponemal antibodies during Treponema pallidum infection: evidence from a rabbit model. J Infect Dis. 2018;218:835–43.

3. Lin LR, Gao ZX, Lin Y, Zhu XZ, Liu W, Liu D, Gao K, Tong ML, Zhang HL, Liu LL. Akt, mTOR and NF-κB pathway activation in Treponema pallidum stimulates M1 macrophages. Int Immunopharmacol. 2018;59:181–6.

4. Lin LR, Xiao Y, Liu W, Chen YY, Zhu XZ, Gao ZX, Gao K, Tong ML, Zhang HL, Li SL. Development of tissue inflammation accompanied by NLRP3 inflammasome activation in rabbits infected with Treponema pallidum strain Nichols. BMC Infect Dis. 2018;18(1):101.

5. Kim JH, Sohn HJ, Yoo JK, Kang H, Seong GS, Chwae YJ, Kim K, Park S, Shin HJ. NLRP3 Inflammasome activation in THP-1 target cells triggered by pathogenic Naegleria fowleri. Infect Immun. 2016;84(9):2422–8.

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