The genomics of desmoplastic small round cell tumor reveals the deregulation of genes related to DNA damage response, epithelial-mesenchymal transition, and immune response

Author:

Devecchi Andrea1,De Cecco Loris1ORCID,Dugo Matteo1,Penso Donata1,Dagrada Gianpaolo2,Brich Silvia2,Stacchiotti Silvia3,Sensi Marialuisa1,Canevari Silvana1,Pilotti Silvana2

Affiliation:

1. Platform of Integrated Biology, Department of Applied Research and Technology Development; Fondazione IRCCS Istituto Nazionale dei Tumori di Milano; 2133 Milan Italy

2. Department of Diagnostic Pathology and Laboratory Medicine; Fondazione IRCCS Istituto Nazionale dei Tumori di Milano; 20133 Milan Italy

3. Department of Medical Oncology; Fondazione IRCCS Istituto Nazionale dei Tumori di Milano; 20133 Milan Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Associazione Italiana Ricerca Cancro

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference47 articles.

1. Molecular classification of soft tissue sarcomas and its clinical applications;Jain;Int J Clin Exp Pathol,2010

2. Desmoplastic small round cell tumor: characteristics and prognostic factors of 41 patients and review of the literature;Wong;Clin Sarcoma Res.,2013

3. New strategies in sarcoma therapy: linking biology and novel agents;Janeway;Clin Cancer Res.,2012

4. Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumors;Jiang;PLoS ONE,2014

5. Beware of immunohistochemistry-report of a cytokeratin-, desmin- and INI-1-negative pelvic desmoplastic small round cell tumor in a 51 year old woman;Soon;Int J Clin Exp Pathol,2015

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