Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases
Link
http://link.springer.com/content/pdf/10.1186/1471-2334-1-17.pdf
Reference54 articles.
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2. Neurath AR, Strick N, Li Y-Y, Lin K, Jiang S: Design of a "microbicide" for prevention of sexually transmitted diseases using "inactive" pharmaceutical excipients. Biologicals. 1999, 27: 11-21. 10.1006/biol.1998.0169.
3. Gyotoku T, Aurelian L, Neurath AR: Cellulose acetate phthalate (CAP): an 'inactive' pharmaceutical excipient with antiviral activity in the mouse model of genital herpesvirus infection. A ntivir Chem Chemother. 1999, 10: 327-332.
4. Neurath AR, Li YY, Mandeville R, Richard L: In vitro activity of a cellulose acetate phthalate topical cream against organisms associated with bacterial vaginosis. J Antimicrob Chemother. 2000, 45: 713-714. 10.1093/jac/45.5.713.
5. Manson KH, Wyand MS, Miller C, Neurath AR: The effect of a cellulose acetate phthalate topical cream on vaginal transmission of SIV in rhesus monkeys. Antimicrob Agents Chemother. 2000, 44: 3199-3202. 10.1128/AAC.44.11.3199-3202.2000.
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