Profiling of DNA damage and repair pathways in small cell lung cancer reveals a suppressive role in the immune landscape
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Molecular Medicine
Link
https://link.springer.com/content/pdf/10.1186/s12943-021-01432-5.pdf
Reference15 articles.
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2. Nong J, Gong Y, Guan Y, Yi X, Yi Y, Chang L, et al. Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer. Nat Commun. 2018;9:3114.
3. Park S, Lee H, Lee B, Lee S-H, Sun J-M, Park W-Y, et al. DNA damage response and repair pathway alteration and its association with tumor mutation burden and platinum-based chemotherapy in SCLC. J Thorac Oncol. 2019;14:1640–50.
4. Sun Z, Chen J, Aakre J, Marks RS, Garces YY, Jiang R, et al. Genetic variation in glutathione metabolism and DNA repair genes predicts survival of small-cell lung cancer patients. Ann Oncol. 2010;21:2011–6.
5. Tlemsani C, Takahashi N, Pongor L, Rajapakse VN, Tyagi M, Wen X, et al. Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies. Sci Transl Med. 2021;13:eabc7488.
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