A dream deferred: the rise and fall of recombinant activated protein C
Author:
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine
Reference7 articles.
1. Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
2. Errors in the approval process and post-marketing evaluation of drotrecogin alfa (activated) for the treatment of severe sepsis
3. Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock
4. Stopping Randomized Trials Early for Benefit and Estimation of Treatment EffectsSystematic Review and Meta-regression Analysis
5. Effectiveness and safety of drotrecogin alfa (activated) for severe sepsis: a meta-analysis and metaregression
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1. Comprehensive literature review of protein C concentrate use in patients with severe congenital protein C deficiency;Research and Practice in Thrombosis and Haemostasis;2024-08
2. The role of G protein-coupled receptor in neutrophil dysfunction during sepsis-induced acute respiratory distress syndrome;Frontiers in Immunology;2023-02-20
3. Organ-specific effects on inflammation and apoptosis of recombinant human activated protein C in a murine model of sepsis;European Journal of Inflammation;2017-07-26
4. Neutrophil dysregulation during sepsis: an overview and update;Journal of Cellular and Molecular Medicine;2017-02-28
5. Beyond the Golden Hours;Clinics in Chest Medicine;2016-06
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