Abstract
AbstractNauclea officinalis (N. officinalis), a medicinal plant of the genus Nauclea in the family Rubiaceae, is used in the treatment of fever, pneumonia, pharyngolaryngitis, and enteritis in China. Extracts of N. officinalis include alkaloids, phenolic acids, pentacyclic triterpenoids, and flavonoids, which exert all kinds of pharmacological effects, for instance anti-inflammatory, anti-tumor, antibacterial, and antiviral and therefore show good effectiveness. To gain a comprehensive and deep understanding, the medicinal chemistry and chemical biology of N. officinalis are summarized in this review to provide a theoretical basis. The pharmacological effects were reviewed to provide evidence or insights into potential opportunities for further studies and medicinal exploitation of N. officinalis.
Funder
Scientific and technological innovation project of China Academy of Chinese Medical Sciences
National Key R&D Program of China
Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine
The Fundamental Research Funds for the Central public welfare research institutes
Publisher
Springer Science and Business Media LLC
Subject
Complementary and alternative medicine,Pharmacology
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