PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma-Reference-Cited by-同舟云学术

PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma

Published:2016-03-08 Issue:1 Volume:14 Page:
ISSN:1479-5876
Container-title:Journal of Translational Medicine
language:en
Short-container-title:J Transl Med

Author:

Babichev Yael,Kabaroff Leah,Datti Alessandro,Uehling David,Isaac Methvin,Al-awar Rima,Prakesch Michael,Sun Ren X.,Boutros Paul C.,Venier Rosemarie,Dickson Brendan C.,Gladdy Rebecca A.

Funder

Ontario Institute for Cancer Research (CA)

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://link.springer.com/content/pdf/10.1186/s12967-016-0814-z

Reference47 articles.

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2. Sinha S, Peach AH. Diagnosis and management of soft tissue sarcoma. BMJ. 2010;341:c7170.

3. Yang J, et al. Genetic aberrations in soft tissue leiomyosarcoma. Cancer Lett. 2009;275(1):1–8.

4. Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer. 2002;2(7):489–501.

5. Hernando E, et al. The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. Nat Med. 2007;13(6):748–53.

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