Prevalent bee venom genes evolved before the aculeate stinger and eusociality
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Published:2023-10-23
Issue:1
Volume:21
Page:
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ISSN:1741-7007
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Container-title:BMC Biology
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language:en
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Short-container-title:BMC Biol
Author:
Koludarov IvanORCID, Velasque Mariana, Senoner Tobias, Timm Thomas, Greve Carola, Hamadou Alexander Ben, Gupta Deepak Kumar, Lochnit Günter, Heinzinger Michael, Vilcinskas Andreas, Gloag Rosalyn, Harpur Brock A., Podsiadlowski Lars, Rost Burkhard, Jackson Timothy N. W., Dutertre Sebastien, Stolle Eckart, von Reumont Björn M.
Abstract
Abstract
Background
Venoms, which have evolved numerous times in animals, are ideal models of convergent trait evolution. However, detailed genomic studies of toxin-encoding genes exist for only a few animal groups. The hyper-diverse hymenopteran insects are the most speciose venomous clade, but investigation of the origin of their venom genes has been largely neglected.
Results
Utilizing a combination of genomic and proteo-transcriptomic data, we investigated the origin of 11 toxin genes in 29 published and 3 new hymenopteran genomes and compiled an up-to-date list of prevalent bee venom proteins. Observed patterns indicate that bee venom genes predominantly originate through single gene co-option with gene duplication contributing to subsequent diversification.
Conclusions
Most Hymenoptera venom genes are shared by all members of the clade and only melittin and the new venom protein family anthophilin1 appear unique to the bee lineage. Most venom proteins thus predate the mega-radiation of hymenopterans and the evolution of the aculeate stinger.
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Developmental Biology,Plant Science,General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,Physiology,Ecology, Evolution, Behavior and Systematics,Structural Biology,Biotechnology
Reference127 articles.
1. Oeyen JP, Baa-Puyoulet P, Benoit JB, Beukeboom LW, Bornberg-Bauer E, Buttstedt A, et al. Sawfly genomes reveal evolutionary acquisitions that fostered the mega-radiation of parasitoid and eusocial Hymenoptera. Lavrov D, editor. Genome Biol Evol. 2020;12(7):1099–188. 2. Casewell NR, Wüster W, Vonk FJ, Harrison RA, Fry BG. Complex cocktails: the evolutionary novelty of venoms. Trends Ecol Evol. 2013;28(4):219–29. 3. von Reumont BM, Anderluh G, Antunes A, Ayvazyan N, Beis D, Caliskan F, et al. Modern venomics—current insights, novel methods, and future perspectives in biological and applied animal venom research. GigaScience. 2022;11:giac048. 4. Wang T, Zhao M, Rotgans BA, Ni G, Dean JFD, Nahrung HF, et al. Proteomic analysis of the venom and venom sac of the woodwasp, Sirex noctilio - towards understanding its biological impact. J Proteomics. 2016;146:195–206. 5. Piek T. Venoms of the Hymenoptera. London: Academic Press Inc. (London) Ltd.; 1986.
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