Classification model of amino acid sequences prone to aggregation of therapeutic proteins
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
http://link.springer.com/content/pdf/10.1186/s40203-016-0019-4.pdf
Reference30 articles.
1. Agrawal NJ, Kumar S, Wang X. Aggregation in protein-based biotherapeutics: computational studies and tools to identify aggregation-prone regions. J Pharm Sci. 2011;100:5081–95.
2. Chennamsetty N, Voynov V, Kayser V, Helk B, Trout B. Design of therapeutic proteins with enhanced stability. PNAS. 2009;106:11937–42.
3. Datta-Mannan A, Witcher DR, Tang Y, Watkins J, Wroblewski VJ. Monoclonal antibody clearance. Impact of modulating the interaction of IgG with the neonatal Fc receptor. J Biol Chem. 2007;282:1709–17.
4. De Groot AS, Cousens L, Mingozzi F, Martin W. Tregitope peptides: the active pharmaceutical ingredient of IVIG? Clin Dev Immunol. 2013. doi: 10.1155/2013/493138 .
5. Dostalek M, Gardner I, Gurbaxani BM, Rose RH, Chetty M. Pharmacokinetics, pharmacodynamics and physiologically-based pharmacokinetic modelling of monoclonal antibodies. Clin Pharmacokinet. 2012;52:83–124.
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