Author:
Helt Gregg A,Nicol John W,Erwin Ed,Blossom Eric,Blanchard Steven G,Chervitz Stephen A,Harmon Cyrus,Loraine Ann E
Abstract
Abstract
Background
Visualization software can expose previously undiscovered patterns in genomic data and advance biological science.
Results
The Genoviz Software Development Kit (SDK) is an open source, Java-based framework designed for rapid assembly of visualization software applications for genomics. The Genoviz SDK framework provides a mechanism for incorporating adaptive, dynamic zooming into applications, a desirable feature of genome viewers. Visualization capabilities of the Genoviz SDK include automated layout of features along genetic or genomic axes; support for user interactions with graphical elements (Glyphs) in a map; a variety of Glyph sub-classes that promote experimentation with new ways of representing data in graphical formats; and support for adaptive, semantic zooming, whereby objects change their appearance depending on zoom level and zooming rate adapts to the current scale. Freely available demonstration and production quality applications, including the Integrated Genome Browser, illustrate Genoviz SDK capabilities.
Conclusion
Separation between graphics components and genomic data models makes it easy for developers to add visualization capability to pre-existing applications or build new applications using third-party data models. Source code, documentation, sample applications, and tutorials are available at http://genoviz.sourceforge.net/.
Publisher
Springer Science and Business Media LLC
Subject
Applied Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Structural Biology
Reference16 articles.
1. Aldhous P: Managing the genome data deluge. Science 1993, 262(5133):502–503. 10.1126/science.8211171
2. Sonnhammer EL: Genome informatics: taming the avalanche of genomic data. Genome Biol 2005, 6(1):301. 10.1186/gb-2004-6-1-301
3. Hoon S, Ratnapu KK, Chia JM, Kumarasamy B, Juguang X, Clamp M, Stabenau A, Potter S, Clarke L, Stupka E: Biopipe: a flexible framework for protocol-based bioinformatics analysis. Genome Res 2003, 13(8):1904–1915.
4. Cline MS, Kent WJ: Understanding genome browsing. Nat Biotechnol 2009, 27(2):153–155. 10.1038/nbt0209-153
5. Helt GA, Lewis S, Loraine AE, Rubin GM: BioViews: Java-based tools for genomic data visualization. Genome Res 1998, 8(3):291–305.
Cited by
22 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献