Methylmercury toxic mechanism related to protein degradation and chemokine transcription-Reference-Cited by-同舟云学术

Methylmercury toxic mechanism related to protein degradation and chemokine transcription

Published:2020-07-17 Issue:1 Volume:25 Page:
ISSN:1342-078X
Container-title:Environmental Health and Preventive Medicine
language:en
Short-container-title:Environ Health Prev Med

Author:

Lee Jin-Yong,Hwang Gi-Wook,Naganuma Akira,Satoh Masahiko

Abstract

AbstractMethylmercury is an environmental pollutant that causes neurotoxicity. Recent studies have reported that the ubiquitin-proteasome system is involved in defense against methylmercury toxicity through the degradation of proteins synthesizing the pyruvate. Mitochondrial accumulation of pyruvate can enhance methylmercury toxicity. In addition, methylmercury exposure induces several immune-related chemokines, specifically in the brain, and may cause neurotoxicity. This summary highlights several molecular mechanisms of methylmercury-induced neurotoxicity.

Publisher

Springer Science and Business Media LLC

Subject

Public Health, Environmental and Occupational Health,General Medicine

Link

https://link.springer.com/content/pdf/10.1186/s12199-020-00868-3.pdf

Reference35 articles.

1. Harada M. Minamata disease: methylmercury poisoning in Japan caused by environmental pollution. Crit Rev Toxicol. 1995;25:1–24. https://doi.org/10.3109/10408449509089885.

2. Randall PM, Chattopadhyay S. Mercury contaminated sediment sites-an evaluation of remedial options. Environ Res. 2013;125:131–49. https://doi.org/10.1016/j.envres.2013.01.007.

3. Harding G, Dalziel J, Vass P. Bioaccumulation of methylmercury within the marine food web of the outer Bay of Fundy, Gulf of Maine. PLoS One. 2018;13:e0197220. https://doi.org/10.1371/journal.pone.0197220.

4. Clarkson TW. The three modern faces of mercury. Environ Health Perspect. 2002;110(Suppl 1):11–23. https://doi.org/10.1289/ehp.02110s111.

5. Risher JF, Murray HE, Prince GR. Organic mercury compounds: human exposure and its relevance to public health. Toxicol Ind Health. 2002;18:109–60. https://doi.org/10.1191/0748233702th138oa.

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Health benefits and health risks of contaminated fish consumption: Current research outputs, research approaches, and perspectives;Heliyon;2024-07

2. Sea anemones, methylmercury, and bacterial infection: A closer look at multiple stressors;Marine Pollution Bulletin;2024-04

3. The Application of Aluminium Powder as an Accumulation Medium of Mercury from Air;Atmosphere;2024-03-18

4. Per- and Polyfluoroalkyl Substances: Impacts on Morphology, Behavior and Lipid Levels in Zebrafish Embryos;Toxics;2024-02-29

5. Estimation of mercury uptake and distinction of corn cultivation in China;Science of The Total Environment;2024-01