DeepCRISPR: optimized CRISPR guide RNA design by deep learning-Reference-Cited by-同舟云学术

DeepCRISPR: optimized CRISPR guide RNA design by deep learning

Published:2018-06-26 Issue:1 Volume:19 Page:
ISSN:1474-760X
Container-title:Genome Biology
language:en
Short-container-title:Genome Biol

Author:

Chuai Guohui,Ma Hanhui,Yan Jifang,Chen Ming,Hong Nanfang,Xue Dongyu,Zhou Chi,Zhu Chenyu,Chen Ke,Duan Bin,Gu Feng,Qu Sheng,Huang Deshuang,Wei Jia,Liu Qi

Publisher

Springer Science and Business Media LLC

Link

http://link.springer.com/content/pdf/10.1186/s13059-018-1459-4.pdf

Reference55 articles.

1. Doench JG, Hartenian E, Graham DB, Tothova Z, Hegde M, Smith I, Sullender M, Ebert BL, Xavier RJ, Root DE. Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation. Nat Biotechnol. 2014;32:1262–7.

2. Doench JG, Fusi N, Sullender M, Hegde M, Vaimberg EW, Donovan KF, Smith I, Tothova Z, Wilen C, Orchard R. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9. Nat Biotechnol. 2016:34(2):184-91.

3. Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA. Multiplex genome engineering using CRISPR/Cas systems. Science. 2013;339:819–23.

4. Doudna JA, Charpentier E. The new frontier of genome engineering with CRISPR-Cas9. Science. 2014;346:1258096.

5. Xu H, Xiao T, Chen C-H, Li W, Meyer C, Wu Q, Wu D, Cong L, Zhang F, Liu JS. Sequence determinants of improved CRISPR sgRNA design. Genome Res. 2015:25(8):1147-57.

Cited by 311 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The transformative potential of AI-driven CRISPR-Cas9 genome editing to enhance CAR T-cell therapy;Computers in Biology and Medicine;2024-11

2. Learning to quantify uncertainty in off-target activity for CRISPR guide RNAs;Nucleic Acids Research;2024-09-14

3. Codon usage and expression-based features significantly improve prediction of CRISPR efficiency;npj Systems Biology and Applications;2024-09-03

4. Overcoming CRISPR-Cas9 off-target prediction hurdles: A novel approach with ESB rebalancing strategy and CRISPR-MCA model;PLOS Computational Biology;2024-09-03

5. PI3K/AKT confers intrinsic and acquired resistance to pirtobrutinib in chronic lymphocytic leukemia;Leukemia Research;2024-09