A manifesto for the future of ICU trials
Author:
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine
Link
http://link.springer.com/content/pdf/10.1186/s13054-020-03393-5.pdf
Reference15 articles.
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3. Abrams D, Montesi SB, Moore SKL, Manson DK, Klipper KM, Case MA, Brodie D, Beitler JR. Powering bias and clinically important treatment effects in randomized trials of critical illness. Crit Care Med. 2020;48(12):1710–9.
4. Harhay MO, Wagner J, Ratcliffe SJ, Bronheim RS, Gopal A, Green S, Cooney E, Mikkelsen ME, Kerlin MP, Small DS, Halpern SD. Outcomes and statistical power in adult critical care randomized trials. Am J Respir Crit Care Med. 2014;189(12):1469–78.
5. RECOVERY Collaborative Group, Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. Dexamethasone in hospitalized patients with Covid-19—preliminary report. N Engl J Med. 2020;17:NEJMoa2021436. https://doi.org/10.1056/NEJMoa2021436.
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