Liberal versus conservative oxygen therapy in critically ill patients: using the fragility index to determine robust results
Author:
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine
Link
http://link.springer.com/content/pdf/10.1186/s13054-018-2165-z.pdf
Reference20 articles.
1. O’Driscoll BR, Howard LS, Earis J, et al. British Thoracic Society guideline for oxygen use in adults in healthcare and emergency settings. Thorax. 2017;72(suppl 1):ii1–90.
2. Chu DK, Kim LH, Young PJ, et al. Mortality and morbidity in acuyely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systemaic review and meta-analysis. Lancet. 2018;391:1693–705.
3. Walsh M, Srinathan SK, McAuley DF, et al. The statistical significance of randomized controlled trial results is frequently fragile: a case for a fragility index. J Clin Epidemiol. 2014;67:622–8.
4. Ridgeon EE, Young PJ, Bellomo R, et al. The fragility index in multicenter randomized controlled critical care trials. Crit Care Med. 2016;44:1278–84.
5. Girardis M, Busani S, Damiani E, et al. Effect of conservative vs conventional oxygen therapy on mortality among patients in an intensive care unit: the oxygen-ICU randomized clinical trial. JAMA. 2016;316:1583–9.
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