The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index-Reference-Cited by-同舟云学术

The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index

Published:2014-06 Issue:6 Volume:67 Page:622-628
ISSN:0895-4356
Container-title:Journal of Clinical Epidemiology
language:en
Short-container-title:Journal of Clinical Epidemiology

Author:

Walsh Michael,Srinathan Sadeesh K.,McAuley Daniel F.,Mrkobrada Marko,Levine Oren,Ribic Christine,Molnar Amber O.,Dattani Neil D.,Burke Andrew,Guyatt Gordon,Thabane Lehana,Walter Stephen D.,Pogue Janice,Devereaux P.J.

Publisher

Elsevier BV

Subject

Epidemiology

Reference13 articles.

1. Controversy in counting and attributing events in clinical trials;Sackett;N Engl J Med,1979

2. On the psychology of prediction;Kahneman;Psychol Rev,1973

3. Contradicted and initially stronger effects in highly cited clinical research;Ioannidis;JAMA,2005

4. Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2);Woods;Lancet,1992

5. ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58 050 patients with suspected acute myocardial infarction

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