Zonation of the drug-metabolizing enzyme cytochrome P450 3A in infant mice begins in pre-weaning period
Author:
Affiliation:
1. Department of Clinical Pharmacokinetics, Hoshi University
2. Department of Functional Molecule Kinetics Hoshi University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/43/3/43_223/_pdf
Reference12 articles.
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2. Gebhardt, R. and Matz-Soja, M. (2014): Liver zonation: novel aspects of its regulation and its impact on homeostasis. World J. Gastroenterol., 20, 8491-8504.
3. Gluzman, Y. (1981): SV40-transformed simian cells support the replication of early SV40 mutants. Cell, 23, 175-182.
4. Kitaoka, S., Hatogai, J., Iimura, R., Yamamoto, Y., Oba, K., Nakai, M., Kusunoki, Y., Ochiai, W. and Sugiyama, K. (2018): Relationship between Low Midazolam Metabolism by Cytochrome P450 3A in Mice and the High Incidence of Birth Defects. J. Toxicol. Sci., 43, 65-74.
5. Man, K., Kutyavin, V.I. and Chawla, A. (2017): Tissue Immunometabolism: Development, Physiology, and Pathobiology. Cell Metab., 25, 11-26.
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