Climbazole is a new potent inducer of rat hepatic cytochrome P450.
Author:
Affiliation:
1. Departments of Clinical Pharmacy, School of Pharmaceutical Sciences, Showa University
2. Biochemical Toxicology, School of Pharmaceutical Sciences, Showa University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
http://www.jstage.jst.go.jp/article/jts/26/3/26_3_141/_pdf
Reference38 articles.
1. 1-Benzylimidazole induces rat hepatic microsomal epoxide hydrolase with the elevation of its mRNA levels
2. Drug metabolizing enzyme induction by simple diaryl pyridines; 2-substituted isomers selectively increase only conjugation enzyme activities, 4-substituted isomers also induce cytochrome P450
3. Whether cytochrome p450 induction accompanies glucuronosyl and glutathione transferase induction by isomers of dipyridyl appears unrelated to dose and iron chelation properties
4. Funae, Y. and Imaoka, S. (1993): Cytochrome P450 in rodents. In Cytochrome P450: Handbook of Experimental Pharmacology (Schenkman, J.B. and Greim, H., eds.), pp. 221-238, Springer Verlag, Berlin, Heidelberg.
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1. Retinyl propionate and climbazole combination demonstrates clinical improvement to the appearance of hyperpigmentation and deep wrinkling with minimal irritation;International Journal of Cosmetic Science;2017-09-21
2. Climbazole boosts activity of retinoids in skin;International Journal of Cosmetic Science;2017-03-02
3. Chemical-induced coordinated and reciprocal changes in heme metabolism, cytochrome P450 synthesis and others in the liver of humans and rodents;The Journal of Toxicological Sciences;2016
4. Climbazole increases expression of cornified envelope proteins in primary keratinocytes;International Journal of Cosmetic Science;2014-07-25
5. Induction of cytochrome P450 enzymes in rat liver by two conazoles, myclobutanil and triadimefon;Xenobiotica;2007-02
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