Climbazole boosts activity of retinoids in skin

Author:

Adamus J.1,Feng L.1,Hawkins S.1,Kalleberg K.1,Lee J-M.1

Affiliation:

1. Unilever R&D; Trumbull CT 06611 USA

Funder

Unilever

Publisher

Wiley

Subject

Colloid and Surface Chemistry,Dermatology,Drug Discovery,Pharmaceutical Science,Aging,Chemistry (miscellaneous)

Reference44 articles.

1. Auto-regulation of retinoic acid biosynthesis through regulation of retinol esterification in human keratinocytes;Kurlandsky;J. Biol. Chem.,1996

2. Molecular mechanisms of retinoid actions in skin;Fisher;FASEB,1996

3. Retinoid metabolism in the skin;Roos;Pharmacol. Rev.,1998

4. Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation;Kang;J. Invest. Dermatol.,1995

5. Molecular cloning of two human cellular retinoic acid-binding proteins (CRABP): retinoic acid-induced expression of CRABP-II but not CRABP-I in adult human skin in vivo and in skin fibroblasts in vitro;Aström;J. Biol. Chem.,1991

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