Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish

Author:

Liao Xiao-Liang1,Chen Zhi-Feng12ORCID,Zou Ting1,Lin Zhi-Cheng1,Chen Xiao-Fan1,Wang Yujie1,Qi Zenghua1,Cai Zongwei13ORCID

Affiliation:

1. Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, School of Environmental Science and Engineering, Guangdong University of Technology, Guangzhou 510006, China

2. Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety, South China Normal University, Guangzhou 510006, China

3. State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Kowloon, Hong Kong 999077, China

Funder

National Natural Science Foundation of China

Guangdong Province

Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Reference49 articles.

1. Pharmaceuticals and personal care products in the environment: agents of subtle change?

2. European Union. Commission Directive 2008/42/EC of 3 April 2008 last amending Directive 76/768/EEC on the approximation of the laws of the member states relating to cosmetic products, 2008. https://eur-lex.europa.eu/legal-content/EN/ALL/?uri=CELEX%3A32008L0042.

3. Climbazole boosts activity of retinoids in skin

4. ECHA. Justification for the selection of a candidate CoRAP substance (climbazole); European Chemicals Agency, 2013. https://echa.europa.eu/documents/10162/10104ac10108fa-10137d10166-10165ffd-10109a-f10112c14785e10111e.

5. Multimedia fate modeling and risk assessment of a commonly used azole fungicide climbazole at the river basin scale in China

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