Construction of extended and functional bile canaliculi using long-term sandwich-cultured cryopreserved human hepatocytes and the application of hepatocytes for predicting the biliary excretion of pharmaceutical and food-related compounds
-
Published:2023
Issue:5
Volume:48
Page:251-261
-
ISSN:0388-1350
-
Container-title:The Journal of Toxicological Sciences
-
language:en
-
Short-container-title:J. Toxicol. Sci.
Author:
Kitaguchi Takashi1, Horiuchi Shinichiro2, Kuroda Yukie2, Ohno Katsutoshi1, Kobayashi Kazuhiro1, Tanaka Mitsuru1, Ishida Seiichi3
Affiliation:
1. Global Food Safety Institute, Nissin Foods Holdings Co., Ltd. 2. Division of Pharmacology, National Institute of Health Sciences 3. Division of Applied Life Science, Graduate School of Engineering, Sojo University
Publisher
Japanese Society of Toxicology
Reference27 articles.
1. Abe, K., Bridges, A.S. and Brouwer, K.L. (2009): Use of sandwich-cultured human hepatocytes to predict biliary clearance of angiotensin II receptor blockers and HMG-CoA reductase inhibitors. Drug Metab. Dispos., 37, 447-452. 2. Asplund, A., Synnergren, J., Andersson, C.X. and Küppers-Munther, B. (2017): A novel maintenance medium extends the life-span and enables long term applications for both human primary hepatocytes and human pluripotent stem cell derived hepatocytes in conventional 2D cultures. 14th European ISSX Meeting, P57. 3. Bell, C.C., Dankers, A.C., Lauschke, V.M., Sison-Young, R., Jenkins, R., Rowe, C., Goldring, C.E., Park, K., Regan, S.L., Walker, T., Schofield, C., Baze, A., Foster, A.J., Williams, D.P., van de Ven, A.W., Jacobs, F., Houdt, J.V., Lähteenmäki, T., Snoeys, J., Juhila, S., Richert, L. and Ingelman-Sundberg, M. (2018): Comparison of hepatic 2D sandwich cultures and 3D spheroids for long-term toxicity applications: A multicenter study. Toxicol. Sci., 162, 655-666. 4. Dietrich, C.G., de Waart, D.R., Ottenhoff, R., Bootsma, A.H., van Gennip, A.H. and Elferink, R.P. (2001): Mrp2-deficiency in the rat impairs biliary and intestinal excretion and influences metabolism and disposition of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo. Carcinogenesis, 22, 805-811. 5. Fardel, O., Moreau, A., Le Vée, M., Denizot, C. and Parmentier, Y. (2019): Evaluation of drug biliary excretion using sandwich-cultured human hepatocytes. Eur. J. Drug Metab. Pharmacokinet., 44, 13-30.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|