INDUCTION OF HEPATIC CYTOCHROME P450 ISOFORMS BY NICARDIPINE AT THERAPEUTIC DOSES IN SPONTANEOUSLY HYPERTENSIVE RATS
Author:
Affiliation:
1. Department of Molecular Toxicology and COE Program in the 21st Century
2. School of Pharmaceutical Sciences, University of Shizuoka
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
http://www.jstage.jst.go.jp/article/jts/32/1/32_1_79/_pdf
Reference35 articles.
1. Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver
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3. Differential regulation of cytochrome(s) P450 2B1/2 by phenobarbital in hepatic hyperplastic nodules induced by aflatoxin B1 or diethylnitrosamine plus 2-acetylaminofluorene in male F344 rats
4. Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo
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1. Effects of m-nisoldipine on the activity and mRNA expression of four CYP isozymes in rats;Xenobiotica;2017-08-04
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4. Augmentation of 3-methylcholanthrene-induced bioactivation in the human hepatoma cell line HepG2 by the calcium channel blocker nicardipine;Cancer Science;2010-03
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