Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo

Author:

Cui Xiaoming,Thomas Ann,Han Yi,Palamanda Jairam,Montgomery Diana,White Ronald E.,Morrison Richard A.,Cheng K.-C.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference19 articles.

1. Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction;Bowen;Drug Metabolism and Disposition,2000

2. Cytochrome P450 induction in rat hepatocytes assessed by quantitative real-time reverse-transcription polymerase chain reaction and the RNA invasive cleavage assay;Burczynski;Drug Metabolism and Disposition,2001

3. In vitro induction of cytochrome P450 2B1- and 3A1-mRNA and enzyme immunostaining in cryopreserved precision-cut rat liver slices;Glockner;Toxicology,2002

4. In vitro induction of cytochrome P4503A1-mRNA and testosterone hydroxylation in precision-cut liver slices from male and female rats;Glockner;Experimental Toxicologic Pathology,2003

5. Assessment of temporal biochemical and gene transcription changes in rat liver cytochrome P450: utility of real-time quantitative RT-PCR;Goodsaid;Pharmaceutical Research,2003

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