INVESTIGATION OF A HEPATOTOXICITY SCREENING SYSTEM IN PRIMARY CELL CULTURES-"WHAT BIOMARKERS WOULD NEED TO BE ADDRESSED TO ESTIMATE TOXICITY IN CONVENTIONAL AND NEW APPROACHES?"--Reference-Cited by-同舟云学术

INVESTIGATION OF A HEPATOTOXICITY SCREENING SYSTEM IN PRIMARY CELL CULTURES-"WHAT BIOMARKERS WOULD NEED TO BE ADDRESSED TO ESTIMATE TOXICITY IN CONVENTIONAL AND NEW APPROACHES?"-

Published:2005 Issue:1 Volume:30 Page:61-72
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

KIKKAWA Rie¹,YAMAMOTO Toshinori¹,FUKUSHIMA Tamio¹,YAMADA Hiroshi¹,HORII Ikuo¹

Affiliation:

1. Worldwide Safety Sciences, Pfizer Global Research and Development, Nagoya Laboratories, Pfizer Inc.

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

http://www.jstage.jst.go.jp/article/jts/30/1/30_1_61/_pdf

Reference52 articles.

1. The Pathologist and Toxicologist in Pharmaceutical Product Discovery

2. Prolonged Maintenance of Active Cytochrome P-450 in Adult Rat Hepatocytes Co-Cultured with Another Liver Cell Type

3. Gene Expression in Two Hepatic Cell Lines, Cultured Primary Hepatocytes, and Liver Slices Compared to the in Vivo Liver Gene Expression in Rats: Possible Implications for Toxicogenomics Use of in Vitro Systems

4. Fatty Liver Induced by Tetracycline in the Rat

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