An in vivo comet assay of multiple organs (liver, kidney and bone marrow) in mice treated with methyl methanesulfonate and acetaminophen accompanied by hematology and/or blood chemistry
Author:
Affiliation:
1. Toxicology and Pharmacokinetics Laboratories, Pharmaceutical Research Laboratories, Toray Industries, Inc.
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
http://www.jstage.jst.go.jp/article/jts/33/5/33_5_515/_pdf
Reference31 articles.
1. Clapp, N.K., Craig, A.W. and Toya, R.E.Sr. (1968): Oncogenicity by methyl methanesulfonate in male RF mice. Science, 161, 913-914.
2. bcl-2 delay of alkylating agent-induced apoptotic death in a murine hemopoietic stem cell line
3. Farkas, D. and Tannenbaum, S.T. (2005): Characterization of chemically induced hepatotoxicity in collagen sandwiches of rat hepatocytes. Toxicol. Sci., 85, 927-934.
4. Frei, J.V. (1971): Tumor induction by low molecular weight alkylating agents. Chem. Biol. Interactions, 3, 117-121.
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