CHAC1 exacerbates arsenite cytotoxicity by lowering intracellular glutathione levels
-
Published:2023
Issue:9
Volume:48
Page:487-494
-
ISSN:0388-1350
-
Container-title:The Journal of Toxicological Sciences
-
language:en
-
Short-container-title:J. Toxicol. Sci.
Author:
Sumi Daigo1, Taguchi Hiroki1, Takeuchi Kumiko1, Fujishiro Hitomi1
Affiliation:
1. Faculty of Pharmaceutical Sciences, Tokushima Bunri University
Publisher
Japanese Society of Toxicology
Reference33 articles.
1. Aposhian, H.V. and Aposhian, M.M. (2006): Arsenic toxicology: five questions. Chem. Res. Toxicol., 19, 1-15. 2. Chen, D., Chan, R., Waxman, S. and Jing, Y. (2006): Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors. Cancer Res., 66, 11416-11423. 3. Chen, G.Q., Shi, X.G., Tang, W., Xiong, S.M., Zhu, J., Cai, X., Han, Z.G., Ni, J.H., Shi, G.Y., Jia, P.M., Liu, M.M., He, K.L., Niu, C., Ma, J., Zhang, P., Zhang, T.D., Paul, P., Naoe, T., Kitamura, K., Miller, W., Waxman, S., Wang, Z.Y., de The, H., Chen, S.J. and Chen, Z. (1997): Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood, 89, 3345-3353. 4. Chen, G.Q., Zhu, J., Shi, X.G., Ni, J.H., Zhong, H.J., Si, G.Y., Jin, X.L., Tang, W., Li, X.S., Xong, S.M., Shen, Z.X., Sun, G.L., Ma, J., Zhang, P., Zhang, T.D., Gazin, C., Naoe, T., Chen, S.J., Wang, Z.Y. and Chen, Z. (1996): In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins. Blood, 88, 1052-1061. 5. Crawford, R.R., Prescott, E.T., Sylvester, C.F., Higdon, A.N., Shan, J., Kilberg, M.S. and Mungrue, I.N. (2015): Human CHAC1 protein degrades glutathione, and mRNA induction is regulated by the transcription factors ATF4 and ATF3 and a bipartite ATF/CRE regulatory element. J. Biol. Chem., 290, 15878-15891.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|