Trichloroethylene enhances TCR-CD3-induced proliferation of CD8+ rather than CD4+ T cells
Author:
Affiliation:
1. Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/37/2/37_2_381/_pdf
Reference39 articles.
1. Alexander, D.R. (2000): The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell function. Semin. Immunol., 12, 349-359.
2. Blossom, S.J., Doss, J.C., Hennings, L.J., Jernigan, S., Melnyk, S. and James, S.J. (2008): Developmental exposure to trichloroethylene promotes CD4+ T cell differentiation and hyperactivity in association with oxidative stress and neurobehavioral deficits in MRL+/+ mice. Toxicol. Appl. Pharmacol., 231, 344-353.
3. Structural immunology and crystallography help immunologists see the immune system in action: How T and NK cells touch their ligands
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