Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15
Author:
Affiliation:
1. Department of Hygiene and Health Sciences, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
Publisher
Japanese Society of Toxicology
Link
https://www.jstage.jst.go.jp/article/fts/8/1/8_17/_pdf
Reference18 articles.
1. Asada, M., Rauch, A., Shimizu, H., Maruyama, H., Miyaki, S., Shibamori, M., Kawasome, H., Ishiyama, H., Tuckermann, J. and Asahara, H. (2011): DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Kruppel-like factor 15 gene expression. Lab. Invest., 91, 203-215.
2. Cha, J.Y. and Repa, J.J. (2007): The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR. J. Biol. Chem., 282, 743-751.
3. Costet, P., Luo, Y., Wang, N. and Tall, A.R. (2000): Sterol-dependent transactivation of the ABCA1 promoter by the liver X receptor/retinoid X receptor. J. Biol. Chem., 275, 28240-28245.
4. Fujino, T., Sugizaki, K., Kato, R., Beppu, M., Murakami, S., Lee, H., Oshima, T. and Hayakawa, M. (2020): Farnesoid X receptor and liver X receptors regulate Oct3/4 expression by multiple feedback regulating system in normal renal-derived cells and renal adenocarcinoma cells. J. Toxicol. Sci., 45, 25-35.
5. Gan, X., Kaplan, R., Menke, J.G., MacNaul, K., Chen, Y., Sparrow, C.P., Zhou, G., Wright, S.D. and Cai, T.Q. (2001): Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate. J. Biol. Chem., 276, 48702-48708.
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3