A study on the influence of acotiamide hydrochloride hydrate on sex hormones, using a uterotrophic bioassay in rat
Author:
Affiliation:
1. R&D PLANNING, Zeria Pharmaceutical Co., Ltd.
2. Central Research Laboratories, ZERIA Pharmaceutical Co., Ltd.
3. Drug Safety Research Laboratories, Astellas Pharma Inc.
Publisher
Japanese Society of Toxicology
Link
https://www.jstage.jst.go.jp/article/fts/3/1/3_19/_pdf
Reference11 articles.
1. Acofide Tablets 100 mg: Review Report (2013): PMDA Pharmaceuticals and Medical Devices Agency, Japan http://www.pmda.go.jp/english/service/pdf/drugs/acofide_mar2013_e.pdf
2. ICH HARMONISED TRIPARTITE GUIDELINE DOSE SELECTION FOR CARCINOGENICITY STUDIES OF PHARMACEUTICALS S1C(R2) https://www.pmda.go.jp/files/000156959.pdf
3. Kanno, J., Onyon, L., Haseman, J., Fenner-Crisp, P., Ashby, J. and Owens, W. (2001): The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: Phase 1. Environ. Health Perspect., 109, 785-794.
4. Kanno, J., Onyon, L., Peddada, S., Ashby, J., Jacob, E. and Owens, W. (2003a): The OECD program to validate the rat uterotrophic bioassay: Phase two – dose response studies. Environ. Health Perspect., 111, 1530-1549.
5. Kanno, J., Onyon, L., Peddada, S., Ashby, J., Jacob, E. and Owens, W. (2003b): The OECD program to validate the rat uterotrophic bioassay: Phase two – coded single dose studies. Environ. Health Perspect., 111, 1550-1558.
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