Thirteen-week oral toxicity of 1,4-dioxane in rats and mice

Author:

Kano Hirokazu1,Umeda Yumi1,Saito Misae1,Senoh Hideki1,Ohbayashi Hisao1,Aiso Shigetoshi1,Yamazaki Kazunori1,Nagano Kasuke1,Fukushima Shoji1

Affiliation:

1. Japan Bioassay Research Center, Japan Industrial Safety and Health Association

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Reference40 articles.

1. Thirteen‐week Inhalation Toxicity of p ‐Dichlorobenzene in Mice and Rats

2. American Conference of Governmental Industrial Hygienists (ACGIH) (2001): 1,4-Dioxane. Documentation of the Threshold Limit Values and Biological Exposure Indices. ACGIH, Cincinnati, OH.

3. Argus, M.F., Arcos, J.C. and Hoch-Ligeti, C. (1965): Studies on the carcinogenic activity of protein-denaturing agents: Hepatocarcinogenicity of dioxane. J. Natl. Cancer Inst., 35, 949-958.

4. Argus, M.F., Sohal, R.S., Bryant, G.M.,Hoch-Ligeti, C. and Arcos, J.C. (1973): Dose-response and ultrastructural alterations in dioxane carcinogenesis. Influence of methylcholanthrene on acute toxicity. Europ. J. Cancer, 9, 237-243.

5. Chemical Daily (2006): 1,4-Dioxane. In Chemical Products Handbook 14906. pp. 834-835, The Chemical Daily Co., Tokyo.

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