Early detection of hepatocarcinogens in rats by immunohistochemistry of γ-H2AX
Author:
Affiliation:
1. Division of Pathology, National Institute of Health Sciences
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/48/6/48_323/_pdf
Reference39 articles.
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2. Cohen, S.M., Boobis, A.R., Dellarco, V.L., Doe, J.E., Fenner-Crisp, P.A., Moretto, A., Pastoor, T.P., Schoeny, R.S., Seed, J.G. and Wolf, D.C. (2019): Chemical carcinogenicity revisited 3: risk assessment of carcinogenic potential based on the current state of knowledge of carcinogenesis in humans. Regul. Toxicol. Pharmacol., 103, 100-105.
3. EU. (2002): European Union Risk Assessment Report: 1,4-Dioxane. https://echa.europa.eu/documents/10162/a4e83a6a-c421-4243-a8df-3e84893082aa.
4. Falck, J., Coates, J. and Jackson, S.P. (2005): Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature, 434, 605-611.
5. Furihata, C., Toyoda, T., Ogawa, K. and Suzuki, T. (2018): Using RNA-Seq with 11 marker genes to evaluate 1,4-dioxane compared with typical genotoxic and non-genotoxic rat hepatocarcinogens. Mutat. Res. Genet. Toxicol. Environ. Mutagen., 834, 51-55.
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1. EpCAM and APN expression in combination with γ‐H2AX as biomarkers for detecting hepatocarcinogens in rats;Cancer Science;2023-10-19
2. Mucosal damage and γ-H2AX formation in the rat urinary bladder induced by aromatic amines with structures similar to o-toluidine and o-anisidine;Archives of Toxicology;2023-09-29
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