Development of Fast Disintegration Tablets As Oral Drug Delivery System-A Review

Abstract

Fast disintegrating tablets (FDTs) have received increasing demand from the last few years and the field has become a rapidly growing field in the pharmaceutical industry. Fast disintegrating tablets (FDTs) are those solid doses form which when put on the tongue gets rapidly dissolved, releasing the drug within a few second without need of water. The development of FDTs have been formulated for paediatric, geriatric and bedridden patients and for active patients who are busy and travelling and may not have access to water. Such formulation provide an opportunity for product line extension in the many elderly persons will have difficulties in taking conventional oral doses forms (viz, solution suspensions tablet and capsules) because of hand tremors and dysphagia. This article focused on ideal requirements, need for development of FDTs, challenges in formulations, suitability of drug candidates superdisintegrants employed, various technologies developed for FDTs. Evaluation methods, and various marketed products.