Studies on the Metabolic Fate of M17055 a Novel Diuretic (4): Species Difference in Metabolic Pathway and Identification of Human CYP Isoform Responsible for the Metabolism of M17055-Reference-Cited by-同舟云学术

Studies on the Metabolic Fate of M17055 a Novel Diuretic (4): Species Difference in Metabolic Pathway and Identification of Human CYP Isoform Responsible for the Metabolism of M17055

Published:2002 Issue:1 Volume:17 Page:60-74
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Nakajima Hiroyuki,Nakanishi Takeshi,Nakai Kiyohiko,Matsumoto Shigeki,Ida Keiichi,Ogihara Takuo,Ohzawa Nobuo

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference29 articles.

1. A novel quinolinone diuretic, M12285, and its activation mechanism through sulfate conjugation;Shinkawa;European Journal of Pharmacology,1992

2. Pharmacological properties of the novel highly potent diuretic 7-chloro-2,3-dihydro-1-(2-methylbenzoyl)4(1H)-quinolinone 4-oxime-O-sulfonic acid potassium salt;Shinkawa;Arzneimittel-Forschung/Drug Research,1992

3. Loop and distal actions of a novel diuretic, M17055;Shinkawa;European Journal of Pharmacology,1993

4. Studies on the metabolic fate of M17055, a novel diuretic (1): Plasma concentration and excretion of radioactivity in rat and dog after a single intravenous administration of [14C]M17055;Nakajima;Xenobio. Metabol. and Dispos.,2001

5. Studies on the metabolic fate of M17055, a novel diuretic (2): Tissue distribution and transfer of radioactivity into fetus and milk in rat after a single intravenous administration of [14C]M17055;Nakajima;Xenobio. Metabol. and Dispos.,2001

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3. Studies on the metabolic fate of M17055, a novel diuretic (6). Assessment for drug-drug interactions of M17055 in metabolism, distribution and excretion;Xenobiotica;2002-01

4. Studies on the Metabolic Fate of M17055, a Novel Diuretic (5): Pharmacokinetics and Pharmacodynamics of Unchanged Drug in Rat and Dog After Intravenous Administration of M17055;Drug Metabolism and Pharmacokinetics;2002

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