Affiliation:
1. Ryzhih National Medical Research Center of Coloproctology
2. Ryzhih National Medical Research Center of Coloproctology; Russian Medical Academy of Continuous Professional Education
Abstract
AIM: to develop and validate of the colorectal cancer screening questionnaire.PATIENTS AND METHODS: six hundred ninety seven patients without any significant complaints were prospectively included in study. All patients underwent colonoscopy and specific questionnaire. Regression model was performed to stratificate significance level of definite questions.RESULTS: colorectal cancer (CRC) was diagnosed in 39 (5.6%) patients, benign colon neoplasms — in 283 (40.6%) patients. In the ROC analysis, a cut-off of 23 points divides the group of patients into high and low risk of colorectal neoplasms with a sensitivity of 92.8% and a specificity of 39.2%. The area under the curve was 0.724, which corresponds to the good predictive value.CONCLUSION: the developed questionnaire show good predictive power for high CRC risk patients identification, and can be included in the screening program model.
Publisher
Russian Association of Coloproctology
Subject
Gastroenterology,Oncology,Surgery
Reference19 articles.
1. Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Canc J Clin. 2021; 71(3): 209-249. DOI: 10.3322/caac.21660.
2. Feng Y, Jin H, Guo K, et al. Causes of Death After Colorectal Cancer Diagnosis: A Population-Based Study. Front Oncol. 2021; Mar 30:11:647179. DOI: 10.3389/fonc.2021.647179.
3. Kaprin A.D., Starinsky V.V., Shakhzadova O.A. The state of oncological care for the population of Russia in 2021. Moscow: P.A. Herzen Moscow State Medical Research Institute branch of the Federal State Budgetary Institution “NMIRC” of the Ministry of Health of Russia; 2022, 239 р. (in Russ.).
4. Kaprin A.D., Starinsky V.V., Shakhzadova O.A. Malignant neoplasms in Russiain 2021 (morbidity and mortality). Moscow: P.A.Herzen Moscow State Medical Research Institute – Branch of the Federal State Budgetary Institution "NMIC of Radiology" of the Ministry of Health of Russia, 2022, 252 p. (In Russ.).
5. Hull MA, Rees CJ, Sharp L, et al. A risk-stratified approach to colorectal cancer prevention and diagnosis. Nat Rev Gastroenterol Hepatol. 2020; 17: 773–780. DOI: 10.1038/s41575-020-00368-3.
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献