Exercise, Neurotrophins, and Axon Regeneration in the PNS-Reference-Cited by-同舟云学术

Exercise, Neurotrophins, and Axon Regeneration in the PNS

Published:2014-11 Issue:6 Volume:29 Page:437-445
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

English Arthur W.¹,Wilhelm Jennifer C.²,Ward Patricia J.¹

Affiliation:

1. Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia; and

2. Department of Psychology, College of Charleston, Charleston, South Carolina

Abstract

Electrical stimulation and exercise are treatments to enhance recovery from peripheral nerve injuries. Brain-derived neurotrophic factor and androgen receptor signaling are requirements for the effectiveness of these treatments. Increased neuronal activity is adequate to promote regeneration in injured nerves, but the dosing of activity and its relationship to neurotrophins and sex steroid hormones is less clear. Translation of these therapies will require principles associated with their cellular mechanisms.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00028.2014

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