Changes in pairwise correlations during running reshape global network state in the main olfactory bulb-Reference-Cited by-同舟云学术

Changes in pairwise correlations during running reshape global network state in the main olfactory bulb

Published:2021-05-01 Issue:5 Volume:125 Page:1612-1623
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Chockanathan Udaysankar¹²^ORCID,Crosier Emily J. W.²^ORCID,Waddle Spencer³^ORCID,Lyman Edward³,Gerkin Richard C.⁴^ORCID,Padmanabhan Krishnan¹²⁵^ORCID

Affiliation:

1. Medical Scientist Training Program (MSTP), University of Rochester School of Medicine, Rochester, New York

2. Department of Neuroscience and Neuroscience Graduate Program (NGP), University of Rochester School of Medicine, Rochester, New York

3. Department of Physics, University of Delaware, Newark, Delaware

4. School of Life Sciences, Arizona State University, Tempe, Arizona

5. Center for Visual Sciences, University of Rochester School of Medicine, Rochester, New York

Abstract

The organization and structure of spontaneous population activity in the olfactory system places constraints of how odor information is represented. Using high-density electrophysiological recordings of mitral and tufted cells, we found that running increases the dimensionality of spontaneous activity, implicating higher order interactions among neurons during locomotion. Behavior, thus, flexibly alters neuronal activity at the earliest stages of sensory processing.

Funder

Schmitt Foundation

Cystinosis Research Foundation

HHS | NIH | National Institute of General Medical Sciences

HHS | NIH | National Institute of Mental Health

HHS | NIH | National Institute of Neurological Disorders and Stroke

HHS | NIH | National Institute on Deafness and Other Communication Disorders

National Science Foundation

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience