Divergent selection for feed efficiency in pigs altered the duodenum transcriptomic response to feed intake and its DNA methylation profiles-Reference-Cited by-同舟云学术

Divergent selection for feed efficiency in pigs altered the duodenum transcriptomic response to feed intake and its DNA methylation profiles

Published:2024-05-01 Issue:5 Volume:56 Page:397-408
ISSN:1094-8341
Container-title:Physiological Genomics
language:en
Short-container-title:Physiological Genomics

Author:

Devailly Guillaume¹^ORCID,Fève Katia¹,Saci Safia¹,Sarry Julien¹,Valière Sophie²,Lluch Jérôme²,Bouchez Olivier²,Ravon Laure³,Billon Yvon³,Gilbert Hélène¹,Riquet Juliette¹,Beaumont Martin¹^ORCID,Demars Julie¹

Affiliation:

1. GenPhySE, Université de Toulouse, INRAE, ENVT, Castanet Tolosan, France

2. INRAE, US 1426, GeT-PlaGe, Genotoul, Castanet-Tolosan, France

3. Pig Phenotyping and Innovative Breeding Facility, GenESI, UE1372, INRAE, Surgères, France

Abstract

The duodenum is a key organ for the hunger/satiety loop and nutrient sensing. We investigated how the duodenum transcriptome and DNA methylation profiles are affected by feed intakes in pigs. We observed thousands of changes in gene expression levels between overnight-fasted and fed pigs in high-feed efficiency pig lines, but almost none in the related low-feed efficiency pig line.

Funder

Agence Nationale de la Recherche

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/physiolgenomics.00123.2023

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